abstract：:The limitations of current basal insulin preparations include concerns related to their pharmacokinetic and pharmacodynamic properties, hypoglycaemia, weight gain, and perception of management complexity, including rigid dosing schedules. Insulin degludec (IDeg) is a novel basal insulin with improved pharmacokinetic a...

journal_title：Diabetes research and clinical practice

authors： Vora J,Cariou B,Evans M,Gross JL,Harris S,Landstedt-Hallin L,Mithal A,Rodriguez MR,Meneghini L

更新日期：2015-07-01 00:00:00

abstract：:We studied cognition in the Finnish Diabetes Prevention Study (DPS), a trial of lifestyle intervention that prevented diabetes in persons with impaired glucose tolerance. Cognition was similar in the randomization arms 9 years after the intervention in 364 participants, suggesting that the intervention did not benefit...

journal_title：Diabetes research and clinical practice

authors： Luchsinger JA,Lehtisalo J,Lindström J,Ngandu T,Kivipelto M,Ahtiluoto S,Ilanne-Parikka P,Keinänen-Kiukaanniemi S,Eriksson JG,Uusitupa M,Tuomilehto J,Finnish Diabetes Prevention Study (DPS).

更新日期：2015-06-01 00:00:00

abstract：:This study compared the effects on glycaemic variability and glucose control between saxagliptin and acarbose as add-on therapies for aged T2DM inadequately controlled with metformin alone. The results showed that compared with acarbose-metformin, saxagliptin-metformin was more effective in glucose control with simila...

journal_title：Diabetes research and clinical practice

authors： Wang MM,Lin S,Chen YM,Shu J,Lu HY,Zhang YJ,Xie RY,Zeng LY,Mu PW

更新日期：2015-06-01 00:00:00

abstract：AIMS:Diabetes regimen distress (RD) and depression are related constructs, however the nature of their relationship has not been explored over time, leading to difficulties differentiating between RD and depression and for selection of programs of care. We examined longitudinal associations between RD and depression to...

journal_title：Diabetes research and clinical practice

authors： Hessler D,Fisher L,Strycker LA,Arean PA,Bowyer V

更新日期：2015-05-01 00:00:00

abstract：AIMS:To investigate the insulin requirement profiles during short-term intensive continuous subcutaneous insulin infusion (CSII) in patients with newly diagnosed type 2 diabetes and its relationship with long-term glycemic remission. METHODS:CSII was applied in 104 patients with newly diagnosed type 2 diabetes. Daily ...

journal_title：Diabetes research and clinical practice

authors： Liu L,Ke W,Wan X,Zhang P,Cao X,Deng W,Li Y

更新日期：2015-05-01 00:00:00

abstract：AIMS:To determine whether chronic life stress is differentially associated with quality of life (QoL) for Blacks vs. Hispanics with type 2 diabetes. METHODS:We assessed self-reported chronic stress and QoL in 125 patients with type 2 diabetes who self-identified as either non-Hispanic Black or Hispanic. Separate cross...

journal_title：Diabetes research and clinical practice

authors： Shallcross AJ,Ojie MJ,Chaplin W,Levy N,Odedosu T,Ogedegbe G,Spruill TM

更新日期：2015-04-01 00:00:00

abstract：:United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) was established in 1949 and has delivered health care services for over 65 years. The epidemiological transition in disease burden is changing the context in which UNRWA's health programme operates and poses new challenges that requ...

journal_title：Diabetes research and clinical practice

authors： Shahin Y,Kapur A,Seita A

更新日期：2015-04-01 00:00:00

abstract：AIMS:To determine the prevalence and associates of depression in Aboriginal and Anglo-Celt (AC) Australians with type 2 diabetes. METHODS:Community-based patients were screened using the Patient Health Questionnaire (PHQ-9) as part of detailed assessment. The prevalence of any current depression, major depression and ...

journal_title：Diabetes research and clinical practice

authors： Davis TM,Hunt K,Bruce DG,Starkstein S,Skinner T,McAullay D,Davis WA

更新日期：2015-03-01 00:00:00

abstract：AIMS:TNF-α is a diabetogenic cytokine associated with adverse outcomes during pregnancy that can be counterbalanced by IL-10. We have investigated IL-10 and TNF-α balance at maternal and placental levels in hyperglycemia-associated pregnancies. METHODS:One hundred and ninety-two pregnant women participated, which incl...

journal_title：Diabetes research and clinical practice

authors： Moreli JB,Corrêa-Silva S,Damasceno DC,Sinzato YK,Lorenzon-Ojea AR,Borbely AU,Rudge MV,Bevilacqua E,Calderon IM

更新日期：2015-03-01 00:00:00

abstract：AIMS:Studies have shown that diabetes mellitus disproportionately afflicts persons of low socioeconomic status and that the burden of disease is greatest among the disadvantaged. However, our understanding of educational differences in the control of diabetes and its impact on survival is limited. This study investigat...

journal_title：Diabetes research and clinical practice

authors： Dupre ME,Silberberg M,Willis JM,Feinglos MN

更新日期：2015-03-01 00:00:00

abstract：AIM:The "T1D Exchange Clinic Registry" of 13.316 pediatric patients with type 1 diabetes (T1D) in U.S. recently revealed that most children have HbA1c values above target levels established by the American Diabetes Association (ADA) and the International Society for Pediatric and Adolescent Diabetes (ISPAD). The aim of...

journal_title：Diabetes research and clinical practice

authors： Enes P,Martín-Frías M,Álvarez MÁ,Yelmo R,Alonso M,Barrio R

更新日期：2015-02-01 00:00:00

abstract：AIMS:Metformin is the first-line treatment for most patients with type 2 diabetes but many patients need additional treatment with insulin secretagogues (IS) to achieve glycemic control. We aimed to compare mortality and cardiovascular risk among users of metformin in combination with pharmacologically different ISs. ...

journal_title：Diabetes research and clinical practice

authors： Mogensen UM,Andersson C,Fosbøl EL,Schramm TK,Vaag A,Scheller NM,Torp-Pedersen C,Gislason G,Køber L

更新日期：2015-01-01 00:00:00

abstract：AIM:Explore if social network affects development of prediabetes and type 2 diabetes. METHODS:Individuals with normal glucose tolerance at baseline, 2924 women and 2039 men, aged 35-56 years, were followed-up 8-10 years later by an oral glucose tolerance test. Prediabetes and type 2 diabetes was then evident in 168 an...

journal_title：Diabetes research and clinical practice

authors： Hilding A,Shen C,Östenson CG

更新日期：2015-01-01 00:00:00

abstract：AIMS:Insulin degludec/insulin aspart (IDegAsp) is a soluble co-formulation of IDeg and IAsp. This pan-Asian, 26-week trial investigated efficacy and safety of IDegAsp vs biphasic insulin aspart 30 (BIAsp 30) in Asian adults with type 2 diabetes (T2DM), inadequately controlled on once- or twice-daily (BID) basal, premix...

journal_title：Diabetes research and clinical practice

authors： Kaneko S,Chow F,Choi DS,Taneda S,Hirao K,Park Y,Andersen TH,Gall MA,Christiansen JS,BOOST: Intensify All Trial Investigators.

更新日期：2015-01-01 00:00:00

abstract：AIMS:To enhance the universal coverage of quality diabetes care and overcome disparities in care among different care-provider levels by changing the diabetes care system in Changhua, Taiwan. METHODS:The Changhua Diabetes Shared Care program's second stage commenced in 2004. Two levels of diabetes care were proposed t...

journal_title：Diabetes research and clinical practice

authors： Yeh YP,Chang CJ,Hsieh ML,Wu HT

更新日期：2014-12-01 00:00:00

abstract：AIM:To assess changes in circulating incretin levels and body fat compositions with initial combination therapy with α-glucosidase inhibitor and dipeptidyl peptidase-4 inhibitor in patients with type 2 diabetes (T2D). METHODS:In this multicenter open-label 24-week trial, Japanese over-weight (BMI ≥ 25 kg/m(2)) patient...

journal_title：Diabetes research and clinical practice

authors： Mikada A,Narita T,Yokoyama H,Yamashita R,Horikawa Y,Tsukiyama K,Yamada Y

更新日期：2014-12-01 00:00:00

abstract：AIMS:A20 is a negative regulator of nuclear factor kappa B activation and the central gatekeeper in inflammation and immunity. While its role in type 1 diabetes has been widely studied, its expression level in immune cells from type 2 diabetes (T2D) and latent autoimmune diabetes in adult (LADA) patients remains unclea...

journal_title：Diabetes research and clinical practice

authors： Cheng L,Zhang D,Jiang Y,Deng W,Wu Q,Jiang X,Chen B

更新日期：2014-12-01 00:00:00

abstract：:Fifty-nine women with recent gestational diabetes participated in a randomized controlled trial to assess the feasibility and efficacy of a pragmatic diabetes risk reduction intervention. Intervention participants achieved improvements in energy, total and saturated fats, and carbohydrate intake, but no change in phys...

journal_title：Diabetes research and clinical practice

authors： Smith BJ,Cinnadaio N,Cheung NW,Bauman A,Tapsell LC,van der Ploeg HP

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Endothelial dysfunction in diabetes mellitus (DM) is an important factor in the pathogenesis of micro and macrovascular complications. We aimed to measure soluble endothelial protein C receptor (sEPCR) and high sensitivity C reactive protein (hsCRP) levels as markers of endothelial damage in bo...

journal_title：Diabetes research and clinical practice

authors： Zaghloul A,Al-Bukhari TA,Al-Pakistani HA,Shalaby M,Halawani SH,Bajuaifer N,Teama SH

更新日期：2014-12-01 00:00:00

abstract：:Strategies for management of pre-diabetes within the community setting are needed. An adaptation of the successful Diabetes Prevention Program lifestyle intervention delivered by trained diabetes educators was evaluated. Results indicate that trained diabetes educators offer an important community resource for health ...

journal_title：Diabetes research and clinical practice

authors： Kramer MK,Miller RG,Siminerio LM

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:To investigate the changes of serum anti-aging protein Klotho and neutrophil gelatinase-associated lipocalin (NGAL) levels and their correlation in type 2 diabetes mellitus (T2DM) patients at different stages of diabetic kidney disease (DKD) determined by urinary albuminuria. METHODS:462 cases with T2DM were...

journal_title：Diabetes research and clinical practice

authors： Wu C,Wang Q,Lv C,Qin N,Lei S,Yuan Q,Wang G

更新日期：2014-11-01 00:00:00

abstract：AIMS:Recent data have suggested a relationship between the high-density lipoprotein (HDL) subclass ratio and metabolic syndrome (MetS). However, limited information is available regarding the relationships between the HDL subclass ratio and insulin resistance, associated adipocytokine levels, and MetS components. The a...

journal_title：Diabetes research and clinical practice

authors： Moriyama K,Negami M,Takahashi E

更新日期：2014-11-01 00:00:00

abstract：AIMS:Low-density lipoprotein (LDL)-apheresis removes various molecules including LDL/oxidized LDL and inflammatory cytokines and recovers clinical laboratory parameters. It is not yet known whether these advantages of LDL-apheresis improve the prognosis of patients with diabetic nephropathy accompanied by nephrotic syn...

journal_title：Diabetes research and clinical practice

authors： Sato E,Amaha M,Nomura M,Matsumura D,Ueda Y,Nakamura T

更新日期：2014-11-01 00:00:00

abstract：AIM:Whether exposure to relatively high levels of air pollution is associated with diabetes occurrence remains unclear. We sought to assess and quantify the association between exposure to major air pollutants and risk of type 2 diabetes. METHODS:PubMed and EMBASE databases (through September 2013) were searched using...

journal_title：Diabetes research and clinical practice

authors： Balti EV,Echouffo-Tcheugui JB,Yako YY,Kengne AP

更新日期：2014-11-01 00:00:00

abstract：:Current smoking was associated with low insulin secretion and high 30-min plasma glucose (PG), 60-min PG, and area under the curve of PG, whereas current smoking was not associated with fasting PG and 2-h PG levels in both individuals with normoglycemia and individuals with pre-diabetes in a large-scale community-base...

journal_title：Diabetes research and clinical practice

authors： Morimoto A,Tatsumi Y,Miyamatsu N,Sonoda N,Deura K

更新日期：2014-11-01 00:00:00

abstract：AIMS:Reduced heart rate variability (HRV), an early sign of diabetic cardiovascular autonomic neuropathy (CAN), is associated with worse cardiovascular outcomes. The objective was to evaluate relationships between HRV parameters and three pre-clinical cardiovascular disease markers (left ventricular hypertrophy [LVH], ...

journal_title：Diabetes research and clinical practice

authors： Cardoso CR,Moraes RA,Leite NC,Salles GF

更新日期：2014-10-01 00:00:00

abstract：AIMS:Fibrosis is the final disorder of most chronic kidney disease including diabetic nephropathy (DN), but the mechanisms are not fully understood. The present study aims to determine whether TRB3 participates in fibrogenesis in DN. METHODS:Type1 diabetes was induced in male Wistar rats via intraperitoneal injection ...

journal_title：Diabetes research and clinical practice

authors： Wang W,Sun A,Lv W,Cheng J,Lv S,Liu X,Guan G,Liu G

更新日期：2014-10-01 00:00:00

abstract：AIMS:To investigate serum levels of thyroid stimulating hormone (TSH), anti-thyroid peroxidase antibody (TPO), and 25(OH)D in the presence or absence of metabolic syndrome in an obese population. METHODS:Data from a prospectively generated "Obesity Polyclinic" database that includes socio-demographic characteristics, ...

journal_title：Diabetes research and clinical practice

authors： Agbaht K,Mercan Y,Kutlu S,Alpdemir MF,Sezgin T

更新日期：2014-10-01 00:00:00

abstract：AIMS:This study aims to examine the prevalence, associated risk factors and complications of diabetes, as well management and preventive care in Lebanon, a small, middle-income country of the Mediterranean region. METHODS:Using a comprehensive multi-dimensional questionnaire, a cross-sectional national survey of 2195 ...

journal_title：Diabetes research and clinical practice

authors： Costanian C,Bennett K,Hwalla N,Assaad S,Sibai AM

更新日期：2014-09-01 00:00:00

abstract：AIMS:We evaluated the association of combined use of antidepressants and statins and the risk of new-onset diabetes among high-risk adults. METHODS:We used a retrospective, observational, longitudinal design among adults (age ≥ 22 years) who were diabetes free at baseline and had reported hypertension or hyperlipidemi...

journal_title：Diabetes research and clinical practice

authors： Bhattacharya R,Ajmera M,Bhattacharjee S,Sambamoorthi U

更新日期：2014-08-01 00:00:00

abstract：:It is recognized that a chronic low-grade inflammation and an activation of the immune system are involved in the pathogenesis of obesity-related insulin resistance and type 2 diabetes. Systemic inflammatory markers are risk factors for the development of type 2 diabetes and its macrovascular complications. Adipose ti...

journal_title：Diabetes research and clinical practice

authors： Esser N,Legrand-Poels S,Piette J,Scheen AJ,Paquot N

更新日期：2014-08-01 00:00:00

abstract：AIMS:To (1) determine diabetes patients' acceptance of Internet-based interventions (IBIs) for depression, to (2) examine the effectiveness of an acceptance facilitating intervention (AFI) and to (3) explore subgroup specific effects. METHODS:141 diabetes patients from two inpatient rehabilitation units and one outpat...

journal_title：Diabetes research and clinical practice

authors： Baumeister H,Nowoczin L,Lin J,Seifferth H,Seufert J,Laubner K,Ebert DD

更新日期：2014-07-01 00:00:00

abstract：AIMS:Several published diabetes prediction models include information about family history of diabetes. The aim of this study was to extend the previously developed German Diabetes Risk Score (GDRS) with family history of diabetes and to validate the updated GDRS in the Multinational MONItoring of trends and determinan...

journal_title：Diabetes research and clinical practice

authors： Mühlenbruch K,Ludwig T,Jeppesen C,Joost HG,Rathmann W,Meisinger C,Peters A,Boeing H,Thorand B,Schulze MB

更新日期：2014-06-01 00:00:00

abstract：AIMS:Thiazide diuretics are recommended as first line antihypertensive treatment, but may contribute to new onset diabetes. We aimed to describe change in fasting glucose (FG) during prolonged thiazide treatment in an observational setting. METHODS:We conducted an observational, non-randomized, open label, follow-up s...

journal_title：Diabetes research and clinical practice

authors： Karnes JH,Gong Y,Arwood MJ,Gums JG,Hall KL,Limacher MC,Johnson JA,Cooper-DeHoff RM

更新日期：2014-06-01 00:00:00

abstract：AIMS:To understand the composition of the residual dysglycemia when HbA1c is between 6.5% (48mmol/mol) and 7% (53mmol/mol), representing the definition of diabetes and the recommended treatment goal, respectively. METHODS:One hundred persons with type 2 diabetes and a HbA1c<7% (53mmol/mol), treated with diet alone and...

journal_title：Diabetes research and clinical practice

authors： Monnier L,Colette C,Dejager S,Owens D

更新日期：2014-06-01 00:00:00

abstract：:The lesions of diabetic nephropathy have been considered to be irreversible. Pancreas transplantation is the only available treatment able to restore long-term normoglycemia without exposing the patients to the risks of severe hypoglycemia; thus allowing testing the effects of very long-term euglycemia in preventing, ...

journal_title：Diabetes research and clinical practice

authors： Fioretto P,Barzon I,Mauer M

更新日期：2014-06-01 00:00:00

abstract：AIMS:Diabetes is a major risk factor for heart failure (HF). We examined whether baseline HbA1c level predicts HF incidence independent of other HF risk factors, including baseline cardiac structural and functional abnormalities. METHODS:In patients with type 2 diabetes, multivariable Cox regression models were constr...

journal_title：Diabetes research and clinical practice

authors： Kishimoto I,Makino H,Ohata Y,Tamanaha T,Tochiya M,Kada A,Ishihara M,Anzai T,Shimizu W,Yasuda S,Ogawa H

更新日期：2014-05-01 00:00:00

abstract：AIMS:Although most children with type 1 diabetes do not achieve optimal glycemic control, no systematic method exists to identify and address self-management barriers. This study develops and validates PRISM (Problem Recognition in Illness Self-Management), a survey-based tool for efficiently identifying self-managemen...

journal_title：Diabetes research and clinical practice

authors： Cox ED,Fritz KA,Hansen KW,Brown RL,Rajamanickam V,Wiles KE,Fate BH,Young HN,Moreno MA

更新日期：2014-04-01 00:00:00

abstract：:An earlier age of diagnosis (r=-0.28, p<0.0001) and longer duration of type 2 diabetes (r=0.26, p<0.0001) were each found to correlate with higher HbA1c level, on analysis of a diabetes centre database in people under regular shared care. When combined, these biological variables strongly associate with the current Hb...

journal_title：Diabetes research and clinical practice

authors： Hsieh A,Ong PX,Molyneaux L,McGill MJ,Constantino M,Wu T,Wong J,Yue DK,Twigg SM

更新日期：2014-04-01 00:00:00

abstract：:Type 2 diabetes (T2D), being a complex, multi factorial metabolic disorder, its chronic complications development remains puzzled. In this case report, we describe four novel mutations in Cyt b, ATPase 8, ND1 and ND5 genes' synergistic activity as plausible factors for the secondary complications of a patient with chr...

journal_title：Diabetes research and clinical practice

authors： Elango S,Venugopal S,Thangaraj K,Viswanadha VP

更新日期：2014-03-01 00:00:00